A Clinical and Histopathologic Report of Myeloid Leukosis (ML) in Broiler Breeder in Iran

Seyed Aliousat Hosseini Aliabad


Abstract: There are 3 most important neoplastic diseases of poultry, namely Marek’s disease, caused by a herpes virus, and the avian leukosis & reticuloendotheliosis, caused by retroviruses. Among these tumors, the leukosis sarcoma for their epidemiologic characterizes, vertical transmission, variety of virus subgroups and different clinical forms are very important. A case of myeloid leucosis (ML) was observed in broiler breeder flock in north of IRAN. It was initiated from 14 week old with blood blister (hemangioma) in the skin, eyelid and internal organs like liver, ovary and kidneys. This situation have occurred sporadically and continuous to end of the production period and causes about 1% mortality. By increasing the age of flock especially in production period the enlargement of internal organs like liver, kidney… with diffuse and miliary tumor was seen. Also the skeletal tumors which were creamy in color and affected the inner surface of the sternum, ribs, vertebrae and synsacroma was observed. This form of myelocytoma tumor continued for several months and the mortality rate increased near the peak of production and caused about 4% mortality. The diseases continued for several months and cause mortality and lose of performance. Microscopically the skeletal tumors consist of solid masses of uniformity differentiated mature myelocytes with abundant eosinophilic cytoplasmic granules. The liver involvement consisted of marked accumulations of immature granulated myelocytes around portal areas and in the parenchyma .The histopathologic results showed that the microscopic characteristic of cutaneuse lesions and visceral tumor were in agreement respectively with hemangioma and myelocytoma


: Myeloid leucosis (ML), Histopathology, Broiler breeder, Iran.

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